4-amino-8-fluoro-N-(2-pyrrolidin-1-ylethyl)cinnoline-3-carboxamide

Modify Date: 2024-02-15 17:19:04

4-amino-8-fluoro-N-(2-pyrrolidin-1-ylethyl)cinnoline-3-carboxamide Structure
4-amino-8-fluoro-N-(2-pyrrolidin-1-ylethyl)cinnoline-3-carboxamide structure
Common Name 4-amino-8-fluoro-N-(2-pyrrolidin-1-ylethyl)cinnoline-3-carboxamide
CAS Number 187231-62-5 Molecular Weight 303.33500
Density 1.323g/cm3 Boiling Point 425.5ºC at 760 mmHg
Molecular Formula C15H18FN5O Melting Point N/A
MSDS N/A Flash Point 211.1ºC

 Names

Name 4-amino-8-fluoro-N-(2-pyrrolidin-1-ylethyl)cinnoline-3-carboxamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.323g/cm3
Boiling Point 425.5ºC at 760 mmHg
Molecular Formula C15H18FN5O
Molecular Weight 303.33500
Flash Point 211.1ºC
Exact Mass 303.15000
PSA 84.14000
LogP 2.08670
Vapour Pressure 1.91E-07mmHg at 25°C
Index of Refraction 1.642

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GE3620942
CHEMICAL NAME :
3-Cinnolinecarboxamide, 4-amino-8-fluoro-N-(2-(1-pyrrolidinyl)ethyl)-
CAS REGISTRY NUMBER :
187231-62-5
LAST UPDATED :
199803
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C15-H18-F-N5-O
MOLECULAR WEIGHT :
303.38

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 52,91,1997
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 52,91,1997

 Synonyms

4-AMINO-8-FLUORO-N-(2-(PYRROLIDIN-1-YL)ETHYL)-3-CINNOLINECARBOXAMIDE
4-Amino-8-fluoro-N-(2-(1-pyrrolidinyl)ethyl)-3-cinnolinecarboxamide
3-Cinnolinecarboxamide,4-amino-8-fluoro-N-(2-(1-pyrrolidinyl)ethyl)
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