Multi-kinase-IN-3

Modify Date: 2024-07-20 19:57:29

Multi-kinase-IN-3 structure	Common Name	Multi-kinase-IN-3
	CAS Number	2091950-43-3	Molecular Weight	547.65
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₃H₃₃N₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Multi-kinase-IN-3

Multi-kinase-IN-3 (compound 2) is a potent angiokinase inhibitor. Multi-kinase-IN-3 shows inhibition activity against VEGFR-2 and PDGFRβ, with IC50 values of 58.3 and 55 nM, respectively[1].

Name	Multi-kinase-IN-3

Description	Multi-kinase-IN-3 (compound 2) is a potent angiokinase inhibitor. Multi-kinase-IN-3 shows inhibition activity against VEGFR-2 and PDGFRβ, with IC50 values of 58.3 and 55 nM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PDGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
Target	PDGFRβ:55 ± 2.6 nM (IC50) VEGFR-2:58.3 ± 5.9 nM (IC50)
References	[1]. Qin M, et al. Structural modifications of indolinones bearing a pyrrole moiety and discovery of a multi-kinase inhibitor with potent antitumor activity. Bioorg Med Chem. 2020 Jun 1;28(11):115486.

Molecular Formula	C₃₃H₃₃N₅O₃
Molecular Weight	547.65