Tusamitamab ravtansine

Modify Date: 2024-07-22 19:14:31

Tusamitamab ravtansine Structure
Tusamitamab ravtansine structure
Common Name Tusamitamab ravtansine
CAS Number 2254086-60-5 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tusamitamab ravtansine


Tusamitamab ravtansine (SAR-408701) is a DM4 (HY-12454) anti-CEACAM5 antibody-drug conjugate (ADC). Tusamitamab ravtansine is composed of a humanized monoclonal antibody that binds carcinoembryonic antigen-related cell adhesion molecule-5 (CEACAM5) and a cytotoxic maytansinoid that selectively targets CEACAM5-expressing tumor cells[1].

 Names

Name Tusamitamab ravtansine

 Tusamitamab ravtansine Biological Activity

Description Tusamitamab ravtansine (SAR-408701) is a DM4 (HY-12454) anti-CEACAM5 antibody-drug conjugate (ADC). Tusamitamab ravtansine is composed of a humanized monoclonal antibody that binds carcinoembryonic antigen-related cell adhesion molecule-5 (CEACAM5) and a cytotoxic maytansinoid that selectively targets CEACAM5-expressing tumor cells[1].
Related Catalog
References

[1]. Gazzah A, et al. Safety, pharmacokinetics, and antitumor activity of the anti-CEACAM5-DM4 antibody-drug conjugate tusamitamab ravtansine (SAR408701) in patients with advanced solid tumors: first-in-human dose-escalation study. Ann Oncol. 2022 Apr;33(4):416-425.  

 Chemical & Physical Properties

No Any Chemical & Physical Properties