N-(DBCO-PEG4)-N-Biotin-PEG4-NHS

Modify Date: 2024-02-04 17:29:17

N-(DBCO-PEG4)-N-Biotin-PEG4-NHS structure	Common Name	N-(DBCO-PEG4)-N-Biotin-PEG4-NHS
	CAS Number	2353409-72-8	Molecular Weight	1095.26
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₄H₇₄N₆O₁₆S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of N-(DBCO-PEG4)-N-Biotin-PEG4-NHS

N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-(DBCO-PEG4)-N-Biotin-PEG4-NHS

Description	N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₅₄H₇₄N₆O₁₆S
Molecular Weight	1095.26

Hazard Codes	Xi