Taragarestrant meglumine

Modify Date: 2024-04-03 08:49:45

Taragarestrant meglumine structure	Common Name	Taragarestrant meglumine
	CAS Number	2446618-18-2	Molecular Weight	670.60
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₂H₄₂Cl₂FN₃O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Taragarestrant meglumine

Taragarestrant (D-0502) meglumine is a potent, orally active and selective estrogen receptor degrader (SERD). Taragarestrant meglumine shows potent activity in various ER+ breast cancer cell lines and xenograft models[1][2].

Name	Taragarestrant meglumine

Description	Taragarestrant (D-0502) meglumine is a potent, orally active and selective estrogen receptor degrader (SERD). Taragarestrant meglumine shows potent activity in various ER+ breast cancer cell lines and xenograft models[1][2].
Related Catalog	Signaling Pathways >> Others >> Estrogen Receptor/ERR Research Areas >> Cancer
In Vivo	Taragarestrant (D-0502) exhibits superior PK profiles suitable for clinical development[1].
References	[1]. Lin WY, et, al. Abstract 5776: Pharmacologic and PK/PD study of D-0502: An orally bioavailable SERD with potent antitumor activity in ER-positive breast cancer cell lines and xenograft models. 2018 Jul 1;78(13):5776. [2]. WHO Drug Information. International Nonproprietary Names for Pharmaceutical.

Molecular Formula	C₃₂H₄₂Cl₂FN₃O₇
Molecular Weight	670.60

Taragarestrant meglumine

Use of Taragarestrant meglumine

Names

Taragarestrant meglumine Biological Activity

Chemical & Physical Properties