6-(Dimethylamino)-4,4-diphenyl-3-heptanone

Modify Date: 2024-02-03 15:28:08

6-(Dimethylamino)-4,4-diphenyl-3-heptanone structure	Common Name	6-(Dimethylamino)-4,4-diphenyl-3-heptanone
	CAS Number	297-88-1	Molecular Weight	309.44500
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₇NO	Melting Point	99-100ºC
	MSDS	N/A	Flash Point	N/A

Name	6-(Dimethylamino)-4,4-diphenyl-3-heptanone

Melting Point	99-100ºC
Molecular Formula	C₂₁H₂₇NO
Molecular Weight	309.44500
Exact Mass	309.20900
PSA	20.31000
LogP	4.29200

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MJ5960000

CHEMICAL NAME :: 3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, (+-)-

CAS REGISTRY NUMBER :: 297-88-1

LAST UPDATED :: 199806

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C21-H27-N-O

MOLECULAR WEIGHT :: 309.49

WISWESSER LINE NOTATION :: 2VXR&R&1Y1&N1&1 -(+-)

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 95 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 28 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 28 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Lungs, Thorax, or Respiration - respiratory depression

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 26 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 240 mg/kg

SEX/DURATION :: female 7 day(s) pre-mating - 21 day(s) post-birth

TOXIC EFFECTS :: Reproductive - Effects on Newborn - other neonatal measures or effects Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - behavioral

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 12500 ug/kg

SEX/DURATION :: lactating female 5 day(s) post-birth

TOXIC EFFECTS :: Reproductive - Effects on Newborn - biochemical and metabolic

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - rat Testis

DOSE/DURATION :: 10 umol/L

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 27,123,1978

RIDADR	UN 1544
Packaging Group	III
Hazard Class	6.1(b)