diphenoxylate hydrochloride

Modify Date: 2024-01-08 19:24:56

diphenoxylate hydrochloride structure	Common Name	diphenoxylate hydrochloride
	CAS Number	3810-80-8	Molecular Weight	489.048
	Density	N/A	Boiling Point	602.3ºC at 760mmHg
	Molecular Formula	C₃₀H₃₃ClN₂O₂	Melting Point	220.0-222.5ºC
	MSDS	N/A	Flash Point	318ºC

Name	diphenoxylate hydrochloride
Synonym	More Synonyms

Boiling Point	602.3ºC at 760mmHg
Melting Point	220.0-222.5ºC
Molecular Formula	C₃₀H₃₃ClN₂O₂
Molecular Weight	489.048
Flash Point	318ºC
Exact Mass	488.223053
PSA	53.33000
LogP	6.22318
Water Solubility	Very slightly soluble in water, freely soluble in methylene chloride, sparingly soluble in ethanol (96 per cent).

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NS5300000

CHEMICAL NAME :: Isonipecotic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, hydrochloride

CAS REGISTRY NUMBER :: 3810-80-8

LAST UPDATED :: 199712

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C30-H32-N2-O2.Cl-H

MOLECULAR WEIGHT :: 489.10

WISWESSER LINE NOTATION :: T6NTJ A2XR&R&CN DVO2 DR &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 221 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1633,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1636,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >160 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1636,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3182 No. of Facilities: 105 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 8242 (estimated) No. of Female Employees: 7235 (estimated)

RIDADR	UN 1544
Packaging Group	III
Hazard Class	6.1(b)

Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate hydrochloride (1:1)

DIPHENOXYLATE HYDROCHLORIDE

ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate hydrochloride

4-Piperidinecarboxylic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, hydrochloride (1:1)

DIPHENOXYLATE HYDROCHLORIDE ANTIPERISTAL TIC,ANTI

Ethyl-1-(3-cyan-3,3-diphenylpropyl)-4-phenylpiperidin-4-carboxylathydrochlorid

DIPHENOXYLATE HCL

Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-4-piperidinecarboxylate hydrochloride (1:1)

1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-4-piperidinecarboxylic Acid Ethyl Ester Monohydrochloride

1-(3-cyano-3,3-diphénylpropyl)-4-phénylpipéridine-4-carboxylate d'éthyle chlorhydrate

r1132

4-Ethoxycarbonyl-α,α,4-triphenyl-1-piperidinebutyronitrile, hydrochloride

diphenoxylate hydrochloride

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synonyms