Characterization of in vitro metabolites of JWH-018, JWH-073 and their 4-methyl derivatives, markers of the abuse of these synthetic cannabinoids
Veniero Gambaro, Sebastiano Arnoldi, Stefania Bellucci, Eleonora Casagni, Lucia Dell’Acqua, Laura Fumagalli, Marco Pallavicini, Gabriella Roda, Chiara Rusconi, Ermanno Valoti
Index: J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 957 , 68-76, (2014)
Full Text: HTML
Abstract
• Optimization of a suitable extraction protocol for alkylindoles and their metabolites from biological fluids. • Detection of alkylindoles and their metabolites by means of the GC/MS method adopted by UNODC. • In vitro incubation with human liver microsomes of alkylindoles. • Study of the metabolism of 1-butyl-3-(1-(4-methyl)naphthoyl)indole for the first time.
Related Compounds
Related Articles:
Kafirin adsorption on ion-exchange resins: isotherm and kinetic studies.
2014-08-22
[J. Chromatogr. A. 1356 , 105-16, (2014)]
2014-08-01
[J. Am. Soc. Mass Spectrom. 25(8) , 1421-40, (2014)]
Embryonic development and maternal regulation of murine circadian clock function.
2015-04-01
[Chronobiol. Int. 32(3) , 416-27, (2015)]
Protective role of adenylate cyclase in the context of a live pertussis vaccine candidate.
2014-01-01
[Microbes Infect. 16(1) , 51-60, (2014)]
Coffee silverskin: a possible valuable cosmetic ingredient.
2015-03-01
[Pharm. Biol. 53(3) , 386-94, (2015)]