FEBS Letters
2013-06-05
Mitochondrial dysfunction and nuclear-mitochondrial shuttling of TERT are involved in cell proliferation arrest induced by G-quadruplex ligands
Xin-Ying Zhuang, Yong-Gang Yao
Index: FEBS Lett. 587(11) , 1656-62, (2013)
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Abstract
• DODC is more efficient in cell growth inhibition than TMPyP4. • Both DODC and TMPyP4 cause nuclear-mitochondrial shuttling of TERT. • Perturbation of mitochondrial function may account for the toxicity of DODC.
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