Bioorganic & Medicinal Chemistry Letters
2007-11-15
Syntheses and optimization of new GS39783 analogues as positive allosteric modulators of GABA B receptors.
Sébastien Guery, Philipp Floersheim, Klemens Kaupmann, Wolfgang Froestl
Index: Bioorg. Med. Chem. Lett. 17(22) , 6206-11, (2007)
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Abstract
The optimization of GS39783 into potent, selective, and safe positive allosteric modulators of GABA(B) receptors is presented.
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