Correlation of clinical response (PANSS) and plasma levels of haloperidol and reduced haloperidol in schizophrenia.

J M Leroux, E Elia, M Jacquet, J Pommery, J C Levron, P Bouhours, F Erb, D Sechter

Index: Prog. Neuropsychopharmacol. Biol. Psychiatry 18(2) , 347-53, (1994)

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Abstract

1. The authors attempted to correlate plasma concentrations in H/rH and clinical efficacy from 8 schizophrenic patients (DSM IIIR) on H. 2. No significant correlations were found between H, rH plasma levels and positive and negative subscale for each patient. 3. The authors observed an opposite evolution concerning the mean results between plasma concentrations and PANSS total score.