Chemical Communications 2012-08-25

The palladium-catalyzed cross-coupling reactions of trifluoroethyl iodide with aryl and heteroaryl boronic acid esters.

Apeng Liang, Xinjian Li, Dongfeng Liu, Jingya Li, Dapeng Zou, Yangjie Wu, Yusheng Wu

Index: Chem. Commun. (Camb.) 48(66) , 8273-5, (2012)

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Abstract

The cross-coupling reactions of 1,1,1-trifluoro-2-iodoethane with aryl and heteroaryl boronic acid esters have been successfully achieved. The new protocol allows for a convenient introduction of trifluoroethyl groups into a variety of aryl and heteroaryl moieties under mild conditions.