Acute hemifacial dystonia possibly induced by clebopride.

Domenico Bosco, Massimiliano Plastino, Maria Giovanna Marcello, Pasquale Mungari, Antonietta Fava

Index: Clin. Neuropharmacol. 32(2) , 107-8, (2009)

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Abstract

Dystonic reactions produce twisting and repetitive movements or abnormal posturing. Severe dystonic reactions have been shown to occur in concert with numerous medications. This report details the case of a patient who developed hemifacial dystonia as acute side reaction from administration of clebopride for dyspeptic prophylaxis. When the drug was immediately stopped, the dystonic posture disappeared completely within 2 weeks. The use of clebopride may be associated with not only a reversible or persistent parkinsonism syndrome but also hemifacial dystonia; therefore, attention must be drawn to this possible side effect.