[The efficacy of antihypertension drugs and their combinations in the non-treated hypertension].

V V Ruksin, O V Grishin, M M Chiritso

Index: Med. Tr. Prom. Ekol. (5) , 7-11, (2013)

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Abstract

In case of non-treated hypertension several medications and their combinations were studied (captopril, and moxonidine as such, captopril + nifedipine, captopril + moxonidine). Moxonidine to be more effective in patients with the prevalence of the sympathetic tone, captopril in patients without increased sympathetic activity. At a combination of captopril + nifedipine efficiency of therapy was reduced, and at a combination moxonidine + nifedipine - increased. Beyond that administration of captopril + nifedipine possessed more side effects, as to compare with the moxonidine + nifedipine.