Organic Letters 2006-12-21

Highly enantioselective transfer hydrogenation of fluoroalkyl ketones.

Damjan Sterk, Michel Stephan, Barbara Mohar

Index: Org. Lett. 8 , 5935, (2006)

Full Text: HTML

Abstract

[Structure: see text] The asymmetric transfer hydrogenation of fluoroalkyl ketones mediated by [Ru(eta6-arene)((S,S)-R2NSO2DPEN)] catalysts using HCO2H-Et3N afforded the corresponding alcohols with high ee's and in excellent yields.