Chemistry: A European Journal 2013-07-29

Highly efficient catalytic enantioselective Mannich reaction of malonates with N-tert-butoxycarbonyl imines by using Yb(OTf)3/pybox catalysts at room temperature.

Babak Karimi, Ehsan Jafari, Dieter Enders

Index: Chemistry 19(31) , 10142-5, (2013)

Full Text: HTML

Abstract

Go Mannich! A highly efficient and enantioselective method for the direct asymmetric reaction of dibenzyl malonate with N-tert-butoxycarbonyl aldimines in the presence of Yb(OTf)3 and iPr-pybox complexes is described (see scheme; pybox = pyridine bisoxazoline).Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Related Compounds

Related Articles:

Development of amino acid derivatization reagents for liquid chromatography electrospray ionization mass spectrometric analysis and ionization efficiency measurements.

2015-04-17

[J. Chromatogr. A. 1390 , 62-70, (2015)]

Evaluation of novel fluorogenic substrates for the detection of glycosidases in Escherichia coli and enterococci.

2006-11-01

[J. Appl. Microbiol. 101(5) , 977-85, (2006)]

Synthesis of bone-targeted oestrogenic compounds for the inhibition of bone resorption. Bulman Page PC, et al.

[Tetrahedron 57(9) , 1837-47, (2001)]

More Articles...