In vivo and in vitro studies on the binding nature of terreic acid with macromolecules such as protein and nucleic acids.

T Subramanian, K M Namasivayam, E R Shanmugasundaram

Index: Toxicol. Lett. 10(2-3) , 249-53, (1982)

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Abstract

The binding of terreic acid to macromolecules such as nucleic acids and protein was examined. In vivo studies using [14C]terreic acid showed that radioactivity was incorporated into the protein and nucleic acid fractions of the liver mice. In vitro experiments with human serum showed that [14C]terreic acid bound to the albumin component and spectral studies indicated that terreic acid also combined with hepatic DNA.