Membrane-bound tyrosine aminopeptidase activities in the rat brain throughout the estrous cycle.
J M de Gandarias, J Irazusta, D Fernández, M Gallego, M Silió, L Casis
Index: Life Sci. 59 , 1097-1101, (1996)
Full Text: HTML
Abstract
Puromycin sensitive and insensitive membrane-bound aminopeptidase activity levels during the estrous cycle in several brain areas have been described in this research. We have found the highest aminopeptidase M activity levels during the proetrous stage in the hypothalamus, the amygdala and the pituitary gland. Since this enzyme has been involved in opioid peptide metabolism, it is suggested that aminopeptidase M could play a part in the decrease in the inhibitory influence of the endogenous opioids peptides that participate in the LH surge.
Related Compounds
Related Articles:
2001-03-01
[Phytochemistry 56 , 523-527, (2001)]
1999-10-01
[Arzneimittelforschung 49 , 816-819, (1999)]