Journal of Organic Chemistry 2007-11-23

Pd(quinoline-8-carboxylate)(2) as a low-priced, phosphine-free catalyst for Heck and Suzuki reactions.

Xin Cui, Juan Li, Zhi-Ping Zhang, Yao Fu, Lei Liu, Qing-Xiang Guo

Index: J. Org. Chem. 72 , 9342, (2007)

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Abstract

N,O-Bidentate compounds were systematically evaluated as phosphine-free ligands for Pd-catalyzed C-C bond-formation reactions through kinetic measurements. Pd(quinoline-8-carboxylate)2 was identified as one of the most efficient, yet still low-priced, phosphine-free catalysts for Heck as well as Suzuki reactions of unactivated aryl bromides with high turnover numbers up to ca. 10,000.