Chemistry & Biodiversity 2008-11-01

Synthesis, characterization, and antifungal activity of boron-containing thiosemicarbazones.

Justin W Hicks, Christian B Kyle, Christopher M Vogels, Susan L Wheaton, Felix J Baerlocher, Andreas Decken, Stephen A Westcott

Index: Chem. Biodivers. 5(11) , 2415-22, (2008)

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Abstract

Addition of thiosemicarbazide, 4-allylthiosemicarbazide, and 4-phenylthiosemicarbazide to (formylphenyl)boronic acids affords a series of thiosemicarbazones containing boronic acids. Addition of 2-formylphenylboronic acid to the thiosemicarbazides gave the corresponding cyclic 2,3,1-benzodiazaborines. All new compounds have been investigated for potential antifungal activity.