Synthesis 2011-04-01

Suzuki-Miyaura cross-coupling of 3-pyridyl triflates with 1-alkenyl-2-pinacol boronates.

JamesR Vyvyan, JenniferA DellN_eMeyer, TobyJ Ligon, KelseyK Motanic, HayleyS Wall

Index: Synthesis 2010(21) , 3637-3644, (2010)

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Abstract

Palladium-catalyzed Suzuki-type couplings of 3-pyridyl triflates with alkenyl pinacol boronates proceed in good to excellent yield. Optimized conditions use Pd(PPh(3))(4) (10 mol %) as catalyst with K(3)PO(4) (3 equiv) as base in dioxane.


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