Organic Letters 2006-10-12

Convenient method for the preparation of Weinreb amides via Pd-catalyzed aminocarbonylation of aryl bromides at atmospheric pressure.

Joseph R Martinelli, Dominique M M Freckmann, Stephen L Buchwald

Index: Org. Lett. 8 , 4843, (2006)

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Abstract

[reaction: see text] The direct transformation of aryl bromides into the corresponding Weinreb amides via Pd-catalyzed aminocarbonylation at atmospheric pressure is reported.

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