Bioorganic & Medicinal Chemistry Letters
2006-03-15
Synthesis and evaluation of an N-acylated photoactivatable analogue of glutathione as probe for glutathione-utilizing enzymes.
Dan Bernardi, Eric Battaglia, Gilbert Kirsch
Index: Bioorg. Med. Chem. Lett. 16 , 1601-1604, (2006)
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Abstract
The first synthesis of an N-acylated photoactivatable analogue of reduced glutathione is described. N-(4-Benzoylbenzoyl)glutathione (8) was found to be an inhibitor and a photoaffinity probe of purified rat liver glutathione S-transferases.
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