Convenient ultrasound-mediated synthesis of 1,4-diazabutadienes under solvent-free conditions.

Jing-Yu He, Hong-Xing Xin, Hong Yan, Xiu-Qing Song, Ru-Gang Zhong

Index: Ultrason. Sonochem. 18(1) , 466-9, (2011)

Full Text: HTML

Abstract

An ultrasound-assisted preparation of 1,4-diazabutadienes via smooth condensation of diketones with amines under solvent-free conditions is described. The generality of this method was examined by the synthesized N,N'-diaryl- and N,N'-dialkyl-1,4-diazabutadiene derivatives. In addition to experimental simplicity, the main advantages of the procedure are mild conditions, short reaction time (2-15 min) and high yields (71-98%).Copyright © 2010 Elsevier B.V. All rights reserved.