Chemsuschem Chemistry And Sustainability, Energy & Materials 2012-02-13

Sequential continuous flow processes for the oxidation of amines and azides by using HOF·MeCN.

Christopher B McPake, Christopher B Murray, Graham Sandford

Index: ChemSusChem 5(2) , 312-9, (2012)

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Abstract

The generation and use of the highly potent oxidising agent HOF·MeCN in a controlled single continuous flow process is described. Oxidations of amines and azides to corresponding nitrated systems by using fluorine gas, water and acetonitrile by sequential gas-liquid/liquid-liquid continuous flow procedures are reported.Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.