2-Bromo-4-fluoroaniline
Names
[ CAS No. ]:
1003-98-1
[ Name ]:
2-Bromo-4-fluoroaniline
[Synonym ]:
2-brom-4-fluoranilin
MFCD00042462
Benzenamine, 2-bromo-4-fluoro-
2-Bromo-4-fluoroaniline
2-bromo-4-fluorophenylamine
ZR DF BE
4-fluoro-2-bromo-aniline
2-bromo-4-fluoro-aniline
4-Bromo-4-fluoroaniline
2-Bromo-4-fluorobenzenamine
Chemical & Physical Properties
[ Density]:
1.7±0.1 g/cm3
[ Boiling Point ]:
221.0±0.0 °C at 760 mmHg
[ Melting Point ]:
41
[ Molecular Formula ]:
C6H5BrFN
[ Molecular Weight ]:
190.013
[ Flash Point ]:
104.4±0.0 °C
[ Exact Mass ]:
188.958939
[ PSA ]:
26.02000
[ LogP ]:
2.40
[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.597
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S37/39
[ RIDADR ]:
UN2810
[ WGK Germany ]:
3
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
2921420090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921420090
[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Arch. Pharm. (Weinheim) 347(2) , 142-52, (2014)
2-Bromo-4-fluoroaniline (1) was condensed with ethyl 2-cyano-3-ethoxyacrylate (2) in ethanol to afford 3, which upon refluxing in paraffin oil at 250°C gave 8-bromo-3-cyano-6-fluoroquinoline-4(1H)-one...
Synthesis of fluorescent tetracyclic lactams by a “one pot” three steps palladium-catalyzed borylation, Suzuki coupling (BSC) and lactamization: DNA and polynucleotides binding studies. Queiroz M-JRP, et al.J. Photochem. Photobiol. A: Chem. 190(1) , 45-52, (2007)
An efficient synthesis of enantiomerically pure aromatic-fused N-containing heterocycles from common chiral aziridines. Chan Kim J, et al.
Tetrahedron 66(40) , 8108-14, (2010)