1-Ethyl-1,3-dihydro-2H-benzimidazol-2-one
Names
[ CAS No. ]:
10045-45-1
[ Name ]:
1-Ethyl-1,3-dihydro-2H-benzimidazol-2-one
[Synonym ]:
2H-Benzimidazol-2-one, 1-ethyl-1,3-dihydro-
EINECS 233-148-1
1-Ethyl-1,3-dihydro-2H-benzimidazol-2-one
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.161±0.06 g/cm3
[ Melting Point ]:
122 ºC
[ Molecular Formula ]:
C9H10N2O
[ Molecular Weight ]:
162.189
[ Exact Mass ]:
162.079315
[ PSA ]:
37.79000
[ LogP ]:
1.39
[ Appearance of Characters ]:
powder
[ Index of Refraction ]:
1.566
[ Storage condition ]:
Store at RT
[ Water Solubility ]:
Slightly soluble (1.6 g/L) (25 ºC)
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H319
[ Precautionary Statements ]:
P305 + P351 + P338
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
22-36
[ Safety Phrases ]:
26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Am. J. Physiol. Cell Physiol. 307(5) , C479-92, (2014)
It has been difficult to separate/identify the roles of ClC-2 and CFTR in Cl(-) transport studies. Using pharmacological agents, we aimed to differentiate functionally between ClC-2 and CFTR Cl(-) cha...
Type 2 diabetes: increased expression and contribution of IKCa channels to vasodilation in small mesenteric arteries of ZDF rats.Am. J. Physiol. Heart Circ. Physiol. 307(8) , H1093-102, (2014)
Impaired endothelial function, which is dysregulated in diabetes, also precedes hypertension. We hypothesized that in Type 2 diabetes, the impaired endothelium-dependent relaxation is due to a loss of...
Firing pattern modulation through SK channel current increase underlies neuronal survival in an organotypic slice model of Parkinson's disease.Mol. Neurobiol. 51(1) , 424-36, (2015)
Dopaminergic (DA) neurons in substantia nigra pars compacta (SNc) are vulnerable to excitotoxicity in Parkinson's disease (PD). Neurotoxic stimuli may alter the firing patterns of DA neurons. However,...