ROCK-IN-32

Names

[ CAS No. ]:
1013117-40-2

[ Name ]:
ROCK-IN-32

Biological Activity

[Description]:

ROCK-IN-32 is an effective Rho-kinase inhibitor.

[References]

1. Zhou ZY, Huang B, Li S, Huang XH, Tang JY, Kwan YW, Hoi PM, Lee SM. Sodium tanshinone IIA sulfonate promotes endothelial integrity via regulating VE-cadherin dynamics and RhoA/ROCK-mediated cellular contractility and prevents atorvastatin-induced intracerebral hemorrhage in zebrafish. Toxicol Appl Pharmacol. 2018 May 4;350:32-42. doi: 10.1016/j.taap.2018.04.037. [Epub ahead of print] PubMed PMID: 29730311.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H17Cl2N3O2

[ Molecular Weight ]:
402.28