3,3,5,5-tetramethyl-1-pyrroline n-oxide

Names

[ Name ]:
3,3,5,5-tetramethyl-1-pyrroline n-oxide

[Synonym ]:
3,3,5,5-Tetramethyl-1-pyrroline N-oxide
2,2,4,4-Tetramethyl-3,4-dihydro-2H-pyrrole 1-oxide
2H-Pyrrole, 3,4-dihydro-2,2,4,4-tetramethyl-, 1-oxide
3,4-dihydro-2,2,4,4-tetrametyl pyrrole-1-oxide
3,4-dihydro-2,2,4,4-tetramethyl-2H-pyrrole-1-oxide
MFCD00010542
3,3,5,5-tetramethyl-1-pyrroline-1-oxide

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
251.0±0.0 °C at 760 mmHg

[ Melting Point ]:
58-61 â„ƒ(lit.)

[ Molecular Formula ]:
C₈H₁₅NO

[ Molecular Weight ]:
141.211

[ Flash Point ]:
113.3±11.5 °C

[ Exact Mass ]:
141.115356

[ PSA ]:
28.75000

[ LogP ]:
-0.11

[ Vapour Pressure ]:
0.0±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.475

[ Storage condition ]:
0-6°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Use of 3,3,5,5-tetramethyl-1-pyrroline-1-oxide spin trap for the continuous flow ESR monitoring of hydroxyl radical generation in the ischemic and reperfused myocardium.

Biochem. Biophys. Res. Commun. 164(3) , 1274-80, (1989)

A new approach for in vivo spin trapping and quantitation of oxygen-derived free radicals has been developed using a continuous flow high speed ESR detection system. Spin adducts of OH. were detected ...

The effect of myoglobin on the stability of the hydroxyl-radical adducts of 5,5 dimethyl-1-pyrolline-N-oxide (DMPO), 3,3,5,5 tetramethyl-1-pyrolline-N-oxide (TMPO) and 1-alpha-phenyl-tert-butyl nitrone (PBN) in the presence of hydrogen peroxide.

Free Radic. Res. 20(5) , 327-32, (1994)

The hydroxyl radical adducts of 5,5 dimethyl-1-pyrolline-N-oxide (DMPO) and 3,3,5,5 tetramethyl-1-pyrolline-N-oxide (TMPO) formed in the presence of hydrogen peroxide and FeII are normally quite stabl...

Oxidation of spin-traps by chlorine dioxide (ClO2) radical in aqueous solutions: first ESR evidence of formation of new nitroxide radicals.

Free Radic. Biol. Med. 20(6) , 837-41, (1996)

The reactivities of the chlorine dioxide (ClO2), which is a stable free radical towards some water-soluble spin-traps were investigated in aqueous solutions by an electron spin resonance (ESR) spectro...