Vorolanib

Names

[ Name ]:
Vorolanib

[Synonym ]:
X-082

Biological Activity

[Description]:

Vorolanib (CM082; X-82) is an orally active, multikinase VEGFR/PDGFR inhibitor. Vorolanib minimizes toxicity, disrupts tumor angiogenesis and tumor cell proliferation, and induces of tumor cell death[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PDGFR

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR

[Target]

VEGFR, PDGFR[1]

[References]

[1]. Bendell JC, et al. Phase I, First-in-Human, Dose-Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Vorolanib in Patients with Advanced Solid Tumors. Oncologist. 2019 Apr;24(4):455-e121.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₆FN₅O₃

[ Molecular Weight ]:
439.48

Vorolanib

Names

Biological Activity

Chemical & Physical Properties

Related Compounds