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1-(3-Indolylmethyl)nipecotic acid ethyl ester

Names

[ CAS No. ]:
101602-77-1

[ Name ]:
1-(3-Indolylmethyl)nipecotic acid ethyl ester

[Synonym ]:
1-indol-3-ylmethyl-piperidine-3-carboxylic acid ethyl ester
1-Indol-3-ylmethyl-piperidin-3-carbonsaeure-aethylester

Chemical & Physical Properties

[ Density]:
1.181g/cm3

[ Boiling Point ]:
430.3ºC at 760mmHg

[ Molecular Formula ]:
C17H22N2O2

[ Molecular Weight ]:
286.36900

[ Flash Point ]:
214ºC

[ Exact Mass ]:
286.16800

[ PSA ]:
45.33000

[ LogP ]:
2.88090

[ Vapour Pressure ]:
1.31E-07mmHg at 25°C

[ Index of Refraction ]:
1.606

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QU1986000
CHEMICAL NAME :
Nipecotic acid, 1-(3-indolylmethyl)-, ethyl ester
CAS REGISTRY NUMBER :
101602-77-1
BEILSTEIN REFERENCE NO. :
0291764
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C17-H22-N2-O2
MOLECULAR WEIGHT :
286.41

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
54 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 105,130,1952

Related Compounds