(5α,8β)-3-Methoxy-17-methyl-6,7-didehydro-4,5-epoxymorphinan-8-ol hydrochloride (1:1)

Names

[ CAS No. ]:
102043-42-5

[ Name ]:
(5α,8β)-3-Methoxy-17-methyl-6,7-didehydro-4,5-epoxymorphinan-8-ol hydrochloride (1:1)

[Synonym ]:
PGE2 1,15-lactone
(1R,2R,3S,5R)-2,6,6-trimethylbicyclo[3.1.1]heptane-2,3-diol
(1R,2R,3S,4R)-2,6,6-trimethylcyclo[3.1.1]heptane-2,3-diol
(-)-podorhizol
(-)epi-podorhizol
(-)-pinane-2,3-diol
(-)-prostaglandin E2-1,15-lactone
Pinanediol [INCI]
(-)-2,3-Pinanediol
(1R,2R,3S,5R)-(-)-Pinanediol
(1R,2R,3S,5R)-(-)-2,3-Pinanediol
(-)-cis-Pinane-cis-2,3-diol
(3S,11aR,14R,14aR)-14-hydroxy-3-pentyl-6,7,8,11,11a,13,14,14a-octahydro-3H-cyclopenta[e]oxacyclotridecine-5,12-dione
(1R,2R,3S,5R)-2,6,6-trimethylbicyclo[3.3.1]heptane-2,3-diol
(-)-(1R,2R,3S,5R)-pinane-2,3-diol
(-)-pinanediol
(-)-pseudocodeine,hydrochloride
[1R-(1|A,2|A,3|A,5|A)]-2,6,6-Trimethylbicyclo[3.1.1]heptane-2,3-diol
(-)-Pseudocodein,Hydrochlorid
(-)-2-Hydroxyisopinocampheol

Chemical & Physical Properties

[ Boiling Point ]:
466ºC at 760mmHg

[ Molecular Formula ]:
C₁₈H₂₂ClNO₃

[ Molecular Weight ]:
335.82500

[ Flash Point ]:
235.7ºC

[ Exact Mass ]:
335.12900

[ PSA ]:
41.93000

[ LogP ]:
2.24100

[ Vapour Pressure ]:
1.74E-09mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QD1055000

CHEMICAL NAME :: Morphinan-8-beta-ol, 6,7-didehydro-4,5-alpha-epoxy-3-methoxy-17-methyl-, hydrochloride

CAS REGISTRY NUMBER :: 102043-42-5

LAST UPDATED :: 199009

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C18-H21-N-O3.Cl-H

MOLECULAR WEIGHT :: 335.86

WISWESSER LINE NOTATION :: T B6566 B6/CO 4ABBC R BX HO PN EU GHT&&TTJ DQ JO1 P1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 51,35,1934

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 579 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 66,182,1939