Benzenamine,4-(2-benzothiazolyl)-N,N-dimethyl-

Names

[ CAS No. ]:
10205-56-8

[ Name ]:
Benzenamine,4-(2-benzothiazolyl)-N,N-dimethyl-

[Synonym ]:
MFCD00937700

Biological Activity

[Description]:

Luciferase-IN-1 is a luciferase inhibitor[1].

[Related Catalog]:

Research Areas >> Neurological Disease

[In Vitro]

Luciferase-IN-1 is a Luciferase inhibitor[1].

[References]

[1]. Auld DS, et al. A basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolution. J Med Chem. 2009;52(5):1450-1458.

Chemical & Physical Properties

[ Density]:
1.213g/cm3

[ Boiling Point ]:
414.1ºC at 760mmHg

[ Molecular Formula ]:
C₁₅H₁₄N₂S

[ Molecular Weight ]:
254.35000

[ Flash Point ]:
204.2ºC

[ Exact Mass ]:
254.08800

[ PSA ]:
44.37000

[ LogP ]:
4.02930

[ Vapour Pressure ]:
4.58E-07mmHg at 25°C

[ Index of Refraction ]:
1.683

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DL3820000

CHEMICAL NAME :: Benzothiazole, 2-(p-(dimethylamino)phenyl)-

CAS REGISTRY NUMBER :: 10205-56-8

BEILSTEIN REFERENCE NO. :: 0185488

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C15-H14-N2-S

MOLECULAR WEIGHT :: 254.37

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 8,33,1958

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%