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Methanamine,1-(2-benzothiazolylthio)-N,N-dimethyl-

Names

[ CAS No. ]:
10220-35-6

[ Name ]:
Methanamine,1-(2-benzothiazolylthio)-N,N-dimethyl-

[Synonym ]:
Methanamine,N-dimethyl
USAF PD-65

Chemical & Physical Properties

[ Density]:
1.26g/cm3

[ Boiling Point ]:
320.8ºC at 760mmHg

[ Molecular Formula ]:
C10H12N2S2

[ Molecular Weight ]:
224.34600

[ Flash Point ]:
147.8ºC

[ Exact Mass ]:
224.04400

[ PSA ]:
69.67000

[ LogP ]:
2.90750

[ Vapour Pressure ]:
0.000309mmHg at 25°C

[ Index of Refraction ]:
1.669

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DL3800000
CHEMICAL NAME :
Benzothiazole, 2-(dimethylaminomethyl)thio-
CAS REGISTRY NUMBER :
10220-35-6
LAST UPDATED :
199406
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C10-H12-N2-S2
MOLECULAR WEIGHT :
224.36
WISWESSER LINE NOTATION :
T56 BN DSJ CS1N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1700 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Behavioral - rigidity (including catalepsy)
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 6(7),28,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1520 mg/kg/15W-I
TOXIC EFFECTS :
Vascular - BP lowering not characterized in autonomic section Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 6(7),28,1962

Synthetic Route

Precursor & DownStream


Related Compounds