7-Octynoic acid
Names
Biological Activity
[Description]:
7-Octynoic acid (compound 42) is a PROTAC linker and can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C8H12O2
[ Molecular Weight ]:
140.18000
[ Exact Mass ]:
140.08400
[ PSA ]:
37.30000
[ LogP ]:
1.65470
[ Storage condition ]:
2-8℃
Safety Information
[ HS Code ]:
2916190090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2916190090
[ Summary ]:
2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%