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Procyanidin A1

Names

[ CAS No. ]:
103883-03-0

[ Name ]:
Procyanidin A1

[Synonym ]:
procyanidin A1
Proanthocyanidin A-1
epicatechin-(4β-->8, 2β-->O-->7)-catechin
PROANTHOCYANIDIN A
proanthocyanidin A1

Biological Activity

[Description]:

Procyanidin A1 (Proanthocyanidin A1) is a procyanidin dimer, which inhibits degranulation downstream of protein kinase C activation or Ca2+ influx from an internal store in RBL-213 cells. Procyanidin A1 has antiallergic effects[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[In Vivo]

Procyanidin A1 suppress serum IgE and IgG1 levels in mice-immunized with ovalbumin[2].

[References]

[1]. Tomochika K, et al. Effects of peanut-skin procyanidin A1 on degranulation of RBL-2H3 cells. Biosci Biotechnol Biochem. 2011;75(9):1644-8.

[2]. Takano F, et al. Aqueous extract of peanut skin and its main constituent procyanidin A1 suppress serum IgE and IgG1 levels in mice-immunized with ovalbumin. Biol Pharm Bull. 2007 May;30(5):922-7.

Chemical & Physical Properties

[ Molecular Formula ]:
C30H24O12

[ Molecular Weight ]:
576.50

[ Exact Mass ]:
576.12700

[ PSA ]:
209.76000

[ LogP ]:
2.79350

Related Compounds