3,5-Difluorophenylacetic acid
Names
[ CAS No. ]:
105184-38-1
[ Name ]:
3,5-Difluorophenylacetic acid
[Synonym ]:
MFCD00010316
(3,5-Difluorophenyl)acetic acid
Benzeneacetic acid, 3,5-difluoro-
2-(3,5-difluorophenyl)acetic acid
QV1R CF EF
3,5-Difluorobenzeneacetic acid
3,5-Difluorophenylacetic Acid
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
245.0±25.0 °C at 760 mmHg
[ Melting Point ]:
68-70 °C(lit.)
[ Molecular Formula ]:
C8H6F2O2
[ Molecular Weight ]:
172.129
[ Flash Point ]:
102.0±23.2 °C
[ Exact Mass ]:
172.033585
[ PSA ]:
37.30000
[ LogP ]:
1.65
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.508
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36-S36/37/39-S22-S22/26/36/37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2916399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2916399090
[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Org. Biomol. Chem. 3(13) , 2450-7, (2005)
Inhibition of gamma-secretase, one of the enzymes responsible for the cleavage of the amyloid precursor protein (APP) to produce pathogenic Abeta peptides, is an attractive approach for the treatment ...
Synthesis of a tetrahydroimidazo [2', 1': 2, 3] thiazolo [5, 4-c] pyridine derivative with Met inhibitory activity. Amat M, et al.ARKIVOC 3 , 145-151, (2010)
Synthesis of dihalophenylacetic acids using aromatic nucleophilic substitution strategy. Kowalczyk BA.
Synthesis 1997(12) , 1411-14, (1997)