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2-Naphthalenamine,3-methyl-

Names

[ CAS No. ]:
10546-24-4

[ Name ]:
2-Naphthalenamine,3-methyl-

[Synonym ]:
2-NAPHTHYLAMINE,3-METHYL
3-Amino-2-methyl-naphthalin
2-Amino-3-methylnaphthalene
3-methylnaphthalene-2-amine
3-methyl-2-naphthalenamine
3-methyl-2-naphthylamine
2-Naphthalenamine,3-methyl

Chemical & Physical Properties

[ Density]:
1.106g/cm3

[ Boiling Point ]:
318.2ºC at 760 mmHg

[ Molecular Formula ]:
C11H11N

[ Molecular Weight ]:
157.21200

[ Flash Point ]:
161.6ºC

[ Exact Mass ]:
157.08900

[ PSA ]:
26.02000

[ LogP ]:
3.31160

[ Vapour Pressure ]:
0.000366mmHg at 25°C

[ Index of Refraction ]:
1.671

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QM4025000
CHEMICAL NAME :
2-Naphthylamine, 3-methyl-
CAS REGISTRY NUMBER :
10546-24-4
BEILSTEIN REFERENCE NO. :
2716046
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C11-H11-N
MOLECULAR WEIGHT :
157.23
WISWESSER LINE NOTATION :
L66J CZ D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1800 mg/kg/18W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
CUSCAM Current Science. (Current Science Assoc., Sadashivanagar P.O., Bangalore 560 080, India) V.1- 1932- Volume(issue)/page/year: 33,45,1964
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4100 mg/kg/17W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
CUSCAM Current Science. (Current Science Assoc., Sadashivanagar P.O., Bangalore 560 080, India) V.1- 1932- Volume(issue)/page/year: 33,45,1964
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - hamster
DOSE/DURATION :
4440 mg/kg/94W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors Tumorigenic - tumors at site of application
REFERENCE :
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 67,481,1981 *** REVIEWS *** TOXICOLOGY REVIEW ADCSAJ Advances in Chemistry Series. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) No.1- 1950- Volume(issue)/page/year: 13,271,1970

Synthetic Route

Precursor & DownStream


Related Compounds