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N-acetyloxytocin

Names

[ CAS No. ]:
10551-48-1

[ Name ]:
N-acetyloxytocin

[Synonym ]:
1-{[(4R,7S,10S,13S,16S,19R)-19-Acetamido-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-2-butanyl]-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-L-leucylglycinamide
Glycinamide, 1-[[(4R,7S,10S,13S,16S,19R)-19-(acetylamino)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloeicos-4-yl]carbonyl]-L-prolyl-L-leucyl-

Biological Activity

[Description]:

N-Acetyloxytocin is isolated and characterized in the neurointermediate lobe of the rat pituitary (NIL) and their presence in several brain areas of the rat[1].

[Related Catalog]:

Research Areas >> Endocrinology

[In Vitro]

Nα-acetylation is a post-translational modification of vasopressin (VP), and oxytocin (OT). The acetylated forms arc not restricted to the pineal gland, the tissue in which Nα-acetyl-OT is initially identified, but also occur in other systems producing OT and VP[1].

[References]

[1]. Liu B, et al. N-acetyl-vasopressin- and N-acetyl-oxytocin-like substances: isolation and characterization in the rat neurointermediate pituitary and presence in the brain. J Neuroendocrinol. 1989;1(1):47-52.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
1593.2±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C45H68N12O13S2

[ Molecular Weight ]:
1049.224

[ Flash Point ]:
917.3±34.3 °C

[ Exact Mass ]:
1048.447021

[ LogP ]:
-3.89

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.628

Related Compounds