1,4-Benzoquinone
Names
[ CAS No. ]:
106-51-4
[ Name ]:
1,4-Benzoquinone
[Synonym ]:
2,5-Cyclohexadiene-1,4-dione
p-Benzoquinone,Quinone
para-benzoquinone
Thiophene,5-dibromo
p-quinone
2,5-dibromothiophen
para-quinone
benzoquinone
2,5-dibromo thiophene
MFCD00001591
1,4-Dihydrobenzoquinone
2,5-dibromothiphene
Cyclohexadiene-1,4-dione
1,3-dibromothiophene
1,4-benzo-quinone
Thiophene,2,5-dibromo
2,5-bromothiophene
EINECS 203-405-2
p-benozquinone
p-Benzoquinone
p-dioxobenzene
1,4-Benzoquinone
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
174.0±15.0 °C at 760 mmHg
[ Melting Point ]:
113-115 °C(lit.)
[ Molecular Formula ]:
C6H4O2
[ Molecular Weight ]:
108.095
[ Flash Point ]:
59.3±17.4 °C
[ Exact Mass ]:
108.021126
[ PSA ]:
34.14000
[ LogP ]:
0.26
[ Vapour density ]:
3.73 (vs air)
[ Vapour Pressure ]:
1.2±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.543
[ Stability ]:
Stable, but light sensitive. Incompatible with strong oxidizing agents. Flammable.
[ Water Solubility ]:
10 g/L (25 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DK2625000
- CHEMICAL NAME :
- p-Benzoquinone
- CAS REGISTRY NUMBER :
- 106-51-4
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 60
- MOLECULAR FORMULA :
- C6-H4-O2
- MOLECULAR WEIGHT :
- 108.10
- WISWESSER LINE NOTATION :
- L6V DVJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 130 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 30 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5600 ug/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 8500 ug/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - cyanosis
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 93800 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 296 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 800 mg/kg/29W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Skin and Appendages - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6326 mg/kg/43W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Skin and Appendages - tumors
- TYPE OF TEST :
- Micronucleus test
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Rodent - rabbit Bone marrow
- REFERENCE :
- AJIMD8 American Journal of Industrial Medicine. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1980- Volume(issue)/page/year: 7,485,1985 *** REVIEWS *** ACGIH TLV-TWA 0.44 mg/m3 (0.1 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,255,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,255,1977 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.1 ppm (0.4 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,221,1971 OSHA PEL (Gen Indu):8H TWA 0.1 ppm (0.4 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.1 ppm (0.4 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.1 ppm (0.4 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.1 ppm (0.4 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 0.1 ppm (0.4 mg/m3) JAN 1993 OEL-AUSTRALIA:TWA 0.1 ppm (0.4 mg/m3) JAN 1993 OEL-AUSTRIA:TWA 0.1 ppm (0.4 mg/m3) JAN 1993 OEL-BELGIUM:TWA 0.1 ppm (0.44 mg/m3) JAN 1993 OEL-DENMARK:TWA 0.1 ppm (0.4 mg/m3) JAN 1993 OEL-FINLAND:TWA 0.1 ppm (0.4 mg/m3);STEL 0.3 ppm;Skin JAN 1993 OEL-FRANCE:TWA 0.1 ppm (0.4 mg/m3);STEL 0.3 ppm (1.5 mg/m3) JAN 1993 OEL-GERMANY:TWA 0.1 ppm (0.4 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 0.1 ppm (0.4 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 5 ppm (15 mg/m3) JAN 1993 OEL-RUSSIA:STEL 0.05 mg/m3 JAN 1993 OEL-SWEDEN:TWA 0.1 ppm (0.4 mg/m3);STEL 0.3 ppm (1.3 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 0.1 ppm (0.4 mg/m3);STEL 0.2 ppm (0.8 mg/m3) JAN 1993 OEL-TURKEY:TWA 0.1 ppm (0.4 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 0.1 ppm (0.4 mg/m3);STEL 0.3 ppm JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO QUINONE-air:10H TWA 0.1 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 66950 No. of Facilities: 145 (estimated) No. of Industries: 3 No. of Occupations: 6 No. of Employees: 3292 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 66950 No. of Facilities: 1228 (estimated) No. of Industries: 17 No. of Occupations: 18 No. of Employees: 15511 (estimated) No. of Female Employees: 1274 (estimated)
Safety Information
[ Symbol ]:
GHS06, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301 + H331-H315-H319-H335-H410
[ Precautionary Statements ]:
P261-P273-P301 + P310 + P330-P304 + P340 + P312-P403 + P233-P501
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T:Toxic
[ Risk Phrases ]:
R23/25;R36/37/38;R50
[ Safety Phrases ]:
S26-S28-S45-S61-S28A-S23-S16
[ RIDADR ]:
UN 2587 6.1/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
DK2625000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
2914700090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2914690090
[ Summary ]:
2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
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