3-Bromopropyne
Names
[ CAS No. ]:
106-96-7
[ Name ]:
3-Bromopropyne
[Synonym ]:
1-Propyne, 3-bromo-
3-Bromopropyne [UN2345] [Flammable liquid]
EINECS 203-447-1
3-Bromopropyne
Propargyl Bromide
4-01-00-00964 (Beilstein Handbook Reference)
Propyne, 3-bromo-
γ-Bromoallylene
3-bromoprop-1-yne
3-Bromo-1-propyne
MFCD00000241
g-bromoallylene
propargylbromide
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Boiling Point ]:
90.0±13.0 °C at 760 mmHg
[ Melting Point ]:
-61°C
[ Molecular Formula ]:
C3H3Br
[ Molecular Weight ]:
118.960
[ Flash Point ]:
17.1±14.3 °C
[ Exact Mass ]:
117.941803
[ LogP ]:
1.32
[ Vapour Pressure ]:
64.6±0.2 mmHg at 25°C
[ Index of Refraction ]:
1.485
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UK4375000
- CHEMICAL NAME :
- Propyne, 3-bromo-
- CAS REGISTRY NUMBER :
- 106-96-7
- BEILSTEIN REFERENCE NO. :
- 0605309
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C3-H3-Br
- MOLECULAR WEIGHT :
- 118.97
- WISWESSER LINE NOTATION :
- E2UU1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 53 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BESAAT Bulletin of the Entomological Society of America. (Entomological Soc. of America, 4603 Calvert Rd., College Park, MD 20740) V.1- 1955- Volume(issue)/page/year: 12,161,1966
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 29 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 28ZEAL "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969 Volume(issue)/page/year: 4,76,1969 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7175 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)
Safety Information
[ Symbol ]:
GHS02, GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H301-H304-H315-H319-H335-H336-H361d-H373
[ Precautionary Statements ]:
P210-P261-P281-P301 + P310-P305 + P351 + P338-P331
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
F:Flammable;T:Toxic;
[ Risk Phrases ]:
R11;R25;R36/37/38;R63
[ Safety Phrases ]:
S53-S16-S36/37/39-S45-S37/39-S28A-S26-S62
[ RIDADR ]:
UN 2345 3/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
UK4375000
[ Packaging Group ]:
II
[ Hazard Class ]:
3
[ HS Code ]:
2903399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2903399090
[ Summary ]:
2903399090. brominated,fluorinated or iodinated derivatives of acyclic hydrocarbons. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%
Articles
J. Am. Chem. Soc. 137 , 5629-35, (2015)
Sequence-defined non-natural polyphosphates were prepared using iterative phosphoramidite protocols on a polystyrene solid support. Three monomers were used in this work: 2-cyanoethyl (3-dimethoxytrit...
Blood-brain barrier-permeable fluorone-labeled dieckols acting as neuronal ER stress signaling inhibitors.Biomaterials 61 , 52-60, (2015)
We studied the blood-brain barrier (BBB) permeability and intracellular localization of a fluorescein isothiocyanate (FITC)-labeled dieckol (1) and a rhodamine B-labeled dieckol (7), for exploring the...
Cytotoxic and genotoxic effects mediated by M2 muscarinic receptor activation in human glioblastoma cells.Neurochem. Int. 90 , 261-70, (2015)
Glioblastomas are the most common brain tumors in humans. Previously, we demonstrated that the muscarinic receptor agonist, arecaidine propargyl ester, via M2 receptors, inhibits cell proliferation in...