GLUT4-IN-17

Names

[ Name ]:
GLUT4-IN-17

Biological Activity

[Description]:

A potent, selective glucose transporter 4 (GLUT4) inhibitor with IC450 of 10.8 uM, inhibits MM cell proliferation; reduces ATB-BMPA binding to GLUT4 to a much greater extent than to GLUT1, inhibits 2-DOG uptake in GLUT4-expressing cells.

[References]

References 1. Mishra RK, et al. J Biol Chem. 2015 Jun 5;290(23):14441-53. View Related Products by Target Glucose Transporter (GLUT)

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₁H₃₅N₅O₂

[ Molecular Weight ]:
509.654

Related Compounds

GLUT4-IN-2
FLT3-IN-17
HPK1-IN-17
PRMT5-IN-17
DHODH-IN-17
HBV-IN-17
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
N-[1-(5-chloropyridin-2-yl)piperidin-4-yl]-N-methylcyclopropanesulfonamide
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine
4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide