ethylphosphonic dichloride

Names

[ CAS No. ]:
1066-50-8

[ Name ]:
ethylphosphonic dichloride

[Synonym ]:
MFCD00002073
EINECS 213-918-3
1-dichlorophosphorylethane

Chemical & Physical Properties

[ Density]:
1.376 g/mL at 25 °C(lit.)

[ Boiling Point ]:
71-72 °C12 mm Hg(lit.)

[ Molecular Formula ]:
C₂H₅Cl₂OP

[ Molecular Weight ]:
146.94000

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
145.94600

[ PSA ]:
26.88000

[ LogP ]:
2.67700

[ Vapour Pressure ]:
0.787mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.465(lit.)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TA1780000

CHEMICAL NAME :: Phosphonic dichloride, ethyl-

CAS REGISTRY NUMBER :: 1066-50-8

BEILSTEIN REFERENCE NO. :: 1743286

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C2-H5-Cl2-O-P

MOLECULAR WEIGHT :: 146.94

WISWESSER LINE NOTATION :: OPGG2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#05945

Safety Information

[ Symbol ]:

GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300-H311 + H331-H314

[ Precautionary Statements ]:
P261-P264-P280-P301 + P310-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T

[ Risk Phrases ]:
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed . R34:Causes burns.

[ Safety Phrases ]:
S23-S26-S36/37/39-S45

[ RIDADR ]:
UN 2922 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
TA1780000

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2931900090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2931900090

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Articles

Resolution of chiral phosphate, phosphonate, and phosphinate esters by an enantioselective enzyme library.

J. Am. Chem. Soc. 128(49) , 15892-902, (2006)

An array of 16 enantiomeric pairs of chiral phosphate, phosphonate, and phosphinate esters was used to establish the breadth of the stereoselective discrimination inherent within the bacterial phospho...

Organophosphorus Isocyanates. Haven Jr AC.

J. Am. Chem. Soc. 78(4) , 842-3, (1956)