BOC-L-phenylalanine-d8

Names

[ CAS No. ]:
106881-07-6

[ Name ]:
BOC-L-phenylalanine-d8

[Synonym ]:
Boc-Phe-OH-phenyl-d5-2,3,3-d3
L-Phenyl-d5-alanine-2,3,3-d3,N-t-Boc derivative
MFCD01075441

Biological Activity

[Description]:

BOC-L-phenylalanine-d8 is the deuterium labeled BOC-L-phenylalanine[1].

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Melting Point ]:
85-87ºC(lit.)

[ Molecular Formula ]:
C14H11D8NO4

[ Molecular Weight ]:
273.35

[ Exact Mass ]:
273.18200

[ PSA ]:
75.63000

[ LogP ]:
2.59790

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Related Compounds