1-Propanethiol

Names

[ CAS No. ]:
107-03-9

[ Name ]:
1-Propanethiol

[Synonym ]:
1-Propanediol
FEMA 3521
EINECS 203-455-5
Propan-1-thiol
Propyl Mercaptan
propylmercaptan
Propanethiol
n-C3H7SH
1-propylthiol
1-Propanethiol
n-propylthiol
MERCAPTAN C3
MFCD00004900

Chemical & Physical Properties

[ Density]:
0.8±0.1 g/cm3

[ Boiling Point ]:
67.8±3.0 °C at 760 mmHg

[ Melting Point ]:
-113 °C

[ Molecular Formula ]:
C₃H₈S

[ Molecular Weight ]:
76.161

[ Flash Point ]:
-20.6±0.0 °C

[ Exact Mass ]:
76.034668

[ PSA ]:
38.80000

[ LogP ]:
1.78

[ Vapour density ]:
2.54 (vs air)

[ Vapour Pressure ]:
155.6±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.431

[ Storage condition ]:
Flammables area

[ Water Solubility ]:
immiscible

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TZ7300000

CHEMICAL NAME :: 1-Propanethiol

CAS REGISTRY NUMBER :: 107-03-9

BEILSTEIN REFERENCE NO. :: 1696860

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C3-H8-S

MOLECULAR WEIGHT :: 76.17

WISWESSER LINE NOTATION :: SH3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,171,1958 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1790 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression Behavioral - coma

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,171,1958

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7300 ppm/4H

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory stimulation Behavioral - somnolence (general depressed activity) Sense Organs and Special Senses (Eye) - lacrimation

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,171,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 515 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression Behavioral - coma

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,171,1958

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4010 ppm/4H

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory stimulation Behavioral - somnolence (general depressed activity) Sense Organs and Special Senses (Eye) - chromodacryorrhea

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,171,1958

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H302-H315-H318-H335

[ Precautionary Statements ]:
P210-P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Flammable;Xn:Harmful;N:Dangerousfortheenvironment;

[ Risk Phrases ]:
R11;R21/22;R36/37/38;R50

[ Safety Phrases ]:
S16-S26-S39-S57-S36/37/39-S29

[ RIDADR ]:
UN 2402 3/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
TZ7300000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
29309070

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Surface modification-induced phase transformation of hexagonal close-packed gold square sheets.

Nat. Commun. 6 , 6571, (2015)

Conventionally, the phase transformation of inorganic nanocrystals is realized under extreme conditions (for example, high temperature or high pressure). Here we report the complete phase transformati...

Competitive adsorption of monoclonal antibodies and nonionic surfactants at solid hydrophobic surfaces.

J. Pharm. Sci. 104(2) , 593-601, (2015)

Two monoclonal antibodies from the IgG subclasses one and two were compared in their adsorption behavior with hydrophobic surfaces upon dilution to 10 mg/mL with 0.9% NaCl. These conditions simulate h...

Biodegradation of malodorous thiols by a Brevibacillus sp. strain isolated from a Tunisian phosphate factory.

FEMS Microbiol. Lett. 362 , (2015)

Hydrogen sulfide (H2S) and thiols (RSH) generated by the phosphate industry cause harmful effects on human health and quality of life. The present study aims to investigate and evaluate a bacterial st...