1-Bromo-2-chloroethane
Names
[ CAS No. ]:
107-04-0
[ Name ]:
1-Bromo-2-chloroethane
[Synonym ]:
Chlorobromoethane
1,2-Chlorobromoethane
2-Bromoethyl Chloride
EINECS 203-456-0
ethylenbromchlorid
1-bromo-2-chloroproethane
1-bromo-2-chloro-ethane
1-Brom-2-chlorethan
s-Chlorobromoethane
wellno.436b
2-Chloroethyl Bromide
1-chloro-2-bromoethane
bromo-2-chloroethane
2-bromochloroethane
1-Bromo-2-chloroethane
MFCD00000962
1-Bromo-2-chloroetha
Ethane, 1-bromo-2-chloro-
CH2BrCH2Cl
Chemical & Physical Properties
[ Density]:
1.7±0.1 g/cm3
[ Boiling Point ]:
106.7±0.0 °C at 760 mmHg
[ Melting Point ]:
−18-−14 °C(lit.)
[ Molecular Formula ]:
C2H4BrCl
[ Molecular Weight ]:
143.410
[ Flash Point ]:
9.5±8.5 °C
[ Exact Mass ]:
141.918488
[ LogP ]:
1.61
[ Vapour Pressure ]:
32.6±0.1 mmHg at 25°C
[ Index of Refraction ]:
1.467
[ Water Solubility ]:
7 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KH6500000
- CHEMICAL NAME :
- Ethane, 1-bromo-2-chloro-
- CAS REGISTRY NUMBER :
- 107-04-0
- BEILSTEIN REFERENCE NO. :
- 0605265
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 14
- MOLECULAR FORMULA :
- C2-H4-Br-Cl
- MOLECULAR WEIGHT :
- 143.42
- WISWESSER LINE NOTATION :
- G2E
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 64 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- Specific locus test
- TYPE OF TEST :
- Specific locus test
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TYPE OF TEST :
- DNA damage
MUTATION DATA
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 4 mmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 90,183,1981
Safety Information
[ Symbol ]:
GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H312 + H332-H315-H335-H350
[ Precautionary Statements ]:
P201-P261-P280-P301 + P310-P308 + P313
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T:Toxic
[ Risk Phrases ]:
R23/25;R36/37/38;R68
[ Safety Phrases ]:
S53-S36/37-S45-S38-S36/37/39-S28A
[ RIDADR ]:
UN 2810 6.1/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
KH6500000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
29034980
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2903799090
[ Summary ]:
2903799090 halogenated derivatives of acyclic hydrocarbons containing two or more different halogens。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
Articles
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 983-984 , 55-61, (2015)
The present work is based on a one-step method including derivatization and solid-based disperser liquid-liquid microextraction followed by gas chromatography-flame ionization detection (GC-FID) for t...
Efficient synthesis of furan-2-ylacetates, 7-(alkoxycarbonyl)benzofurans, and 7-(alkoxycarbonyl)-2,3-dihydrobenzofurans based on cyclization reactions of free and masked dianions: a "cyclization/dehydrogenation" strategy.J. Org. Chem. 70 , 10013-10029, (2005)
[reaction: see text] A variety of furan-2-ylacetates have been prepared by dehydrogenation of monocyclic 2-alkylidenetetrahydrofurans, which are readily available by cyclizations of open-chained 1,3-d...
Regio- and diastereoselective synthesis of 2-alkylidenetetrahydrofurans by domino SN/SN' and SN/SN reactions of 1,3-dicarbonyl dianions.J. Org. Chem. 66(18) , 6057-63, (2001)
The domino C,O-cyclodialkylation reaction of dilithiated 1,3-dicarbonyl compounds with 1,4-dibromo-2-butene resulted in regio- and diastereoselective formation of 2-alkylidene-5-vinyltetrahydrofurans....