Glyoxal
Names
[ CAS No. ]:
107-22-2
[ Name ]:
Glyoxal
[Synonym ]:
ODIX
Oxalaldehyde
GLYOXA
ethandial
Biformyl
Ethanedione
Ethanedial,Oxalaldehyde
Diformal
Glyoxal
Biformal
Oxal
GLYOXALE
DIFORMYL
Ethanedial
MFCD00006957
EINECS 203-474-9
1,2-Ethanedione
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
50.0±9.0 °C at 760 mmHg
[ Melting Point ]:
-14 °C
[ Molecular Formula ]:
C2H2O2
[ Molecular Weight ]:
58.036
[ Flash Point ]:
-4.3±4.4 °C
[ Exact Mass ]:
58.005478
[ PSA ]:
34.14000
[ LogP ]:
-0.67
[ Vapour density ]:
>1 (vs air)
[ Vapour Pressure ]:
291.7±0.1 mmHg at 25°C
[ Index of Refraction ]:
1.337
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
miscible
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MD2700000
- CHEMICAL NAME :
- Glyoxal, 40%
- CAS REGISTRY NUMBER :
- 107-22-2
- BEILSTEIN REFERENCE NO. :
- 1732463
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C2-H2-O2
- MOLECULAR WEIGHT :
- 58.04
- WISWESSER LINE NOTATION :
- VHVH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 11/12/1965
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0535504 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2960 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression Nutritional and Gross Metabolic - other changes
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0535124
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2410 mg/m3/4H
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0535127
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Skin and Appendages - dermatitis, other (after systemic exposure)
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0535506
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 10 mL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 11/12/1965 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84477 No. of Facilities: 630 (estimated) No. of Industries: 16 No. of Occupations: 19 No. of Employees: 3846 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84477 No. of Facilities: 2151 (estimated) No. of Industries: 27 No. of Occupations: 40 No. of Employees: 50395 (estimated) No. of Female Employees: 9890 (estimated)
Safety Information
[ Symbol ]:
GHS07, GHS08
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H317-H319-H341
[ Precautionary Statements ]:
P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R20;R36/38;R43;R68
[ Safety Phrases ]:
S36/37
[ RIDADR ]:
UN 1760
[ WGK Germany ]:
1
[ RTECS ]:
MD2700000
[ HS Code ]:
2912190001
Customs
[ HS Code ]: 2912190001
Articles
Biochim. Biophys. Acta 1851 , 1227-39, (2015)
Coq9 is a polypeptide subunit in a mitochondrial multi-subunit complex, termed the CoQ-synthome, required for biosynthesis of coenzyme Q (ubiquinone or Q). Deletion of COQ9 results in dissociation of ...
Structural diversity of supercoiled DNA.Nat. Commun. 6 , 8440, (2015)
By regulating access to the genetic code, DNA supercoiling strongly affects DNA metabolism. Despite its importance, however, much about supercoiled DNA (positively supercoiled DNA, in particular) rema...
Novel HPLC--Fluorescence methodology for the determination of methylglyoxal and glyoxal. Application to the analysis of monovarietal wines "Ribera del Guadiana".Food Chem. 187 , 159-65, (2015)
The determination and quantification of α-dicarbonyl compounds, glyoxal and methylglyoxal, in "Ribera del Guadiana" monovarietal wines (Extremadura, Spain) without sample clean-up has been carried out...