1H-Imidazole-4-carboxylic acid

Names

[ Name ]:
1H-Imidazole-4-carboxylic acid

[Synonym ]:
4-IMidazolecarboxylic Acid
IMIDAZOLE-4-CARBOXYLIC ACID
1H-imidazol-4-ylcarboxylic acid
MFCD00082203
1H-Imidazole-5-carboxylic acid
4,5-imidazoledicarboxylic acid
Imidazol-4-carboxylic acid
RARECHEM AL BE 0762
4-hydroxy imizodale
4-carboxyimidazole
1H-Imidazole-4-carboxylic acid
EINECS 214-017-8

Biological Activity

[Description]:

1H-Imidazole-4-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
495.0±18.0 °C at 760 mmHg

[ Melting Point ]:
294-295 °C(lit.)

[ Molecular Formula ]:
C₄H₄N₂O₂

[ Molecular Weight ]:
112.09

[ Flash Point ]:
253.2±21.2 °C

[ Exact Mass ]:
112.027275

[ PSA ]:
65.98000

[ LogP ]:
0.46

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.617

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NI4001000

CHEMICAL NAME :: Imidazole-4-carboxylic acid

CAS REGISTRY NUMBER :: 1072-84-0

LAST UPDATED :: 198709

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C4-H4-N2-O2

MOLECULAR WEIGHT :: 112.10

WISWESSER LINE NOTATION :: T5M CNJ DVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1650 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PBPHAW Progress in Biochemical Pharmacology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1965- Volume(issue)/page/year: 1,542,1965

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
NI4001000

[ HS Code ]:
2933290090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933290090

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

AICAR administration affects glucose metabolism by upregulating the novel glucose transporter, GLUT8, in equine skeletal muscle.

Vet. J. 205 , 381-6, (2015)

Equine metabolic syndrome is characterized by obesity and insulin resistance (IR). Currently, there is no effective pharmacological treatment for this insidious disease. Glucose uptake is mediated by ...

Hair analysis of histamine and several metabolites in C3H/HeNCrj mice by ultra performance liquid chromatography with electrospray ionization time-of-flight mass spectrometry (UPLC-ESI-TOF-MS): influence of hair cycle and age.

Clin. Chim. Acta 378(1-2) , 122-7, (2007)

According to a previous study, the concentration of HA in the hair of SD rats was similar in each rat and the variation in HA concentration was not so great. However, the concentration in human hair w...

Phosphate ester hydrolysis by hydroxo complexes of trivalent lanthanides stabilized by 4-imidazolecarboxylate.

Inorg. Chem. 45(23) , 9502-17, (2006)

The anion of 4-imidazolecarboxylic acid (HL) stabilizes hydroxo complexes of trivalent lanthanides of the type ML(OH)+ (M = La, Pr) and M2L(n)(OH)(6-n) (M = La, n = 2; M = Pr, n = 2, 3; M = Nd, Eu, Dy...