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Pyridine,3,5-dichloro-2,4-dimethoxy-6-(trichloromethyl)-

Names

[ CAS No. ]:
108030-77-9

[ Name ]:
Pyridine,3,5-dichloro-2,4-dimethoxy-6-(trichloromethyl)-

[Synonym ]:
penclomedine
C8H6Cl5NO2

Chemical & Physical Properties

[ Density]:
1.58g/cm3

[ Boiling Point ]:
345.3ºC at 760mmHg

[ Molecular Formula ]:
C8H6Cl5NO2

[ Molecular Weight ]:
325.40400

[ Flash Point ]:
162.6ºC

[ Exact Mass ]:
322.88400

[ PSA ]:
31.35000

[ LogP ]:
4.23230

[ Vapour Pressure ]:
0.000124mmHg at 25°C

[ Index of Refraction ]:
1.559

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US8600000
CHEMICAL NAME :
Pyridine, 3,5-dichloro-2,4-dimethoxy-6-(trichloromethyl)-
CAS REGISTRY NUMBER :
108030-77-9
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C8-H6-Cl5-N-O2
MOLECULAR WEIGHT :
325.40

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
170 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Blood - changes in bone marrow (not otherwise specified) Blood - other changes
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB91-211151
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>46 mg/kg
TOXIC EFFECTS :
Blood - changes in bone marrow (not otherwise specified) Blood - other changes
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB91-211151 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg/5D-C
TOXIC EFFECTS :
Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB91-211151
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
125 mg/kg/5D-I
TOXIC EFFECTS :
Blood - leukopenia Blood - thrombocytopenia Blood - changes in bone marrow (not otherwise specified)
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB91-11136

Safety Information

[ HS Code ]:
2933399090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%