Mevalonic acid 5-pyrophosphate tetralithium

Names

[ Name ]:
Mevalonic acid 5-pyrophosphate tetralithium

[Synonym ]:
tetralithium,3-hydroxy-3-methyl-5-[oxido(phosphonatooxy)phosphoryl]oxypentanoate

Biological Activity

[Description]:

Mevalonic acid 5-pyrophosphate (5-Diphosphomevalonic acid) tetralithium is an endogenous metabolite of the mevalonate pathway[1].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Mevalonate 5-pyrophosphate decarboxylase, which converts Mevalonic acid 5-pyrophosphate (Mevalonate 5-pyrophosphate) to isopentenyl pyrophosphate (IPP) in an ATP-dependent manner[1].

[References]

[1]. Jeffrey M Vinokur, et al. An Adaptation To Life In Acid Through A Novel Mevalonate Pathway. Sci Rep. 2016 Dec 22;6:39737.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆H₁₀Li₄O₁₀P₂

[ Molecular Weight ]:
331.84900

[ Exact Mass ]:
332.03900

[ PSA ]:
201.76000

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Origins and early evolution of the mevalonate pathway of isoprenoid biosynthesis in the three domains of life.

Mol. Biol. Evol. 28 , 87-99, (2011)

Isoprenoids are a very diverse family of organic compounds widespread in the three domains of life. Although they are produced from the condensation of the same precursors in all organisms (isopenteny...

Procedures for the isolation and quantification of the intermediates of the mevalonic acid pathway.

Anal. Biochem. 215 , 142-149, (1993)

Procedures for the isolation and analysis of all 11 intermediates of the mevalonic acid pathway from acetyl-CoA through geranylgeranyl pyrophosphate were developed. Both acid-labile and base-labile me...